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Quick Answer

Who this guide is for: Patients experiencing lower back pain or sciatica who want to safely heal an L4-L5 disc bulge at home without surgery.

The Quick Answer:
Yes, an L4-L5 disc bulge can heal without surgery. The most effective treatment includes expert-guided physical therapy (physiotherapy)—such as the 1-on-1 virtual sessions at Resolve360—along with short daily walks and safe exercises.

  • What to Strictly Avoid: To prevent worsening, avoid heavy lifting, sit-ups, and forward bending in the early stages.
  • Recovery Timeline: With consistent rehabilitation, recovery typically takes 6 to 12 weeks.

Note: Severe warning signs (like loss of bladder control or worsening leg weakness) require immediate emergency medical care, not exercises.

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What Happens During an L4-L5 Disc Bulge? (And Why Your MRI Doesn't Tell the Whole Story)

An L4-L5 disc bulge means the disc between your fourth and fifth lumbar vertebrae has spread past its normal edge. It can irritate the L5 nerve root, but many bulges cause no pain at all, so your MRI shows only part of the picture.

An L4-L5 disc bulge is when the disc between the fourth and fifth lumbar vertebrae, in the lower back, spreads beyond its normal edge. The disc’s tough outer ring stays intact. That is the difference from a herniation, where inner disc material pushes through a tear in the ring.

 

L4-L5 and L5-S1 are the two lowest discs in the spine. They carry the most load and move the most, so they are the most commonly affected levels.

 

What your MRI does and doesn’t tell you. Disc bulges are very common in people without back pain. A review of 33 studies found bulges on imaging in about 30% of pain-free 20-year-olds, rising to 84% of pain-free 80-year-olds (Brinjikji et al., 2015). A bulge on your report is a finding, not a diagnosis. What matters is whether your symptoms and examination match it.

L4-L5 vs. L5-S1 Symptoms: Is It Just Back Pain or Sciatica Nerve Pain?

An L4-L5 bulge usually sends pain down the outer leg to the top of the foot and big toe (L5 nerve). An L5-S1 bulge usually sends it to the back of the calf, heel and outer foot (S1 nerve). Pain that stays in the back is more likely back pain than sciatica.

 

An L4-L5 bulge can cause back pain alone, or it can irritate a nerve root and cause leg symptoms (sciatica). Common symptoms include:

 

  • Aching or stiffness in the lower back
  • Pain that spreads into the buttock and down the leg
  • Tingling or numbness in the leg or foot
  • Pain that is worse after sitting for a long time, bending or lifting
  • In some people, weakness when lifting the front of the foot or the big toe

 

When leg symptoms appear, where you feel them usually points to the nerve root involved:

Disc Level Nerve Root Where Symptoms Are Felt Possible Weakness
L3–L4 L4 Front of the thigh and inner shin Difficulty straightening the knee
L4–L5 L5 Outer thigh and calf, top of the foot, and big toe Difficulty lifting the foot or big toe, or walking on the heels
L5–S1 S1 Back of the thigh and calf, heel, and outer foot Difficulty rising onto the toes

These patterns overlap, and a clinical examination is needed to confirm them. If your leg pain is the main problem, see our guide to one-to-one online physical therapy for sciatica and leg pain.

What If You Have Multi-Level Bulges (L3-L4, L4-L5, L5-S1)?

Bulges at two or three levels are common on MRI, especially after 40, and they are treated the same way as a single bulge: by your symptoms, not by the number of levels on the report.

 

MRI reports often list L3-L4, L4-L5 and L5-S1 together because age-related disc changes rarely affect just one level. Most of these findings are also seen in people without pain. What matters is which nerve, if any, your symptoms point to. That is usually one level, even when the scan shows several.

 

  • Same first-line plan: staying active, exercise-based physical therapy and pain relief as needed.
  • Exercise choice follows your symptoms. Your physiotherapist tests which movements ease your pain rather than treating each level separately.
  • More levels do not automatically mean surgery. Surgery decisions depend on severe or worsening nerve symptoms that match one specific level.
  • Check thigh symptoms too. If you also have pain at the front of the thigh or weakness straightening the knee, the L3-L4 level (L4 nerve) may be involved; mention it at your assessment.

When Should You Get Urgent Help for L4-L5 Nerve Symptoms?

Bladder or bowel changes, numbness in the saddle area or worsening leg weakness need emergency care the same day.

 

Go to emergency care now (call 911 in the US, or 112 or 108 in India) if you have any of these:

  • New difficulty passing urine, or loss of bladder or bowel control
  • Numbness in the groin, genitals, inner thighs or buttocks (“saddle” area)
  • Weakness in one or both legs that is getting worse
  • Back pain with fever, unexplained weight loss, a history of cancer, or after a significant fall or accident

 

The first two can be signs of cauda equina syndrome, a medical emergency. Exercises and online care are not appropriate until you have been assessed in person.

 

See a doctor within days if pain is getting steadily worse, numbness is spreading, or you cannot sleep or walk because of the pain.

Can an L4-L5 Disc Bulge Heal Without Surgery? (Clinical Evidence & Success Rates)

Yes, in most cases. In a large trial of people with disc-related sciatica, about 95% reported recovery at one year whether or not they had surgery. Surgery mainly made leg pain settle faster.

 

Low back pain guidelines advise that most acute and subacute back pain gets better over time, and recommend non-drug treatment and exercise first (American College of Physicians, 2017; NICE NG59).

 

For disc-related leg pain, a large trial compared early surgery with prolonged non-surgical care. Surgery relieved leg pain faster, but disability over one year was similar, and about 95% of people in both groups reported recovery at one year (Peul et al., 2007).

 

What “healing” means is important. A review of repeat scans found that bulges shrink on imaging much less often than larger herniations: about 13% for bulges compared with 70% for extrusions (Chiu et al., 2015). Pain usually settles anyway, because the irritated nerve and tissues calm down and your back gets stronger. Don’t judge your progress by your next MRI. Judge it by what you can do.

Non-Surgical L4-L5 Disc Bulge Treatment Options Compared

Exercise-based physical therapy and staying active are the first-line treatments. Medicines and injections can ease pain for a while. Traction, back belts and TENS are not recommended.

Overview of common low back pain treatment options, supporting evidence and typical use.
Option What it does Evidence Best used
Staying active and walking Keeps tissues moving and may reduce stiffness. Encouraging normal activity is consistent with guideline-based low back pain care. From day one, within comfort.
Exercise-based physical therapy Identifies movements that may ease symptoms and builds strength, control and activity tolerance. Exercise is recommended in major guidelines, including ACP and NICE, with the approach tailored to the person. The core of treatment for many people, guided by symptoms and function.
Manual therapy (mobilisation, manipulation, massage) May provide short-term pain relief and make movement easier. Some techniques may offer short-term benefit. NICE recommends manual therapy only as part of a package that includes exercise. Alongside exercise, not as a standalone treatment.
Heat May ease muscle tightness and discomfort. ACP includes superficial heat among options for acute or subacute low back pain. In the early phase, or before gentle movement, if comfortable.
Anti-inflammatory medicines (NSAIDs) Can reduce pain and inflammation. Benefits and risks vary. NICE advises considering potential risks and using the lowest effective dose for the shortest possible period. Short term, after checking with a healthcare professional.
Epidural steroid injection May reduce inflammation around an irritated nerve root. Evidence suggests a small, mainly short-term benefit for some people with sciatica. See Pinto et al., 2012. Selected cases of severe sciatica or leg pain; not routine treatment for nonspecific low back pain.
Traction, back belts, TENS and ultrasound Passive treatments intended to relieve symptoms or provide support. NICE advises against these as routine treatments for low back pain or sciatica. Generally not recommended as routine treatments.

Some commonly prescribed tablets for nerve pain (such as gabapentin or pregabalin) and steroid tablets have not shown overall benefit for sciatica, and NICE advises against them. Always discuss medicines with your doctor; this article gives no doses.

How physical therapy helps an L4-L5 disc bulge

Physical therapy finds which movements calm your symptoms, then rebuilds strength and tolerance step by step, which is the approach guidelines recommend first.

 

A good physical therapy plan is built around your symptoms, not around a scan. Your physiotherapist will usually:

 

  1. Assess your symptoms, how far they travel down the leg, and nerve signs such as strength, sensation and reflexes.
  2. Test movements to find a direction that eases your symptoms (for example, gentle backward bending for some people, or flexion-based positions for others). This is often called directional preference.
  3. Settle the pain with positions, walking and short, frequent exercise sessions.
  4. Build strength and control in the trunk and hips, then gradually rebuild sitting, lifting and work or sport tolerance.
  5. Plan for flare-ups so a bad day does not become a setback.

 

If you want this done with a physiotherapist over video, see physical therapy for disc bulge in the USA or physiotherapy for disc bulge in India.

6 Safe Exercises for L4-L5 Disc Bulge Recovery (Plus Movements to Strictly Avoid)

Start with gentle exercises that keep pain the same or pull it back towards your spine. Stop any movement that sends pain further down your leg.

 

No exercise suits everyone with a disc bulge. Use this rule for all of them:

 

  • Good sign: pain stays the same or moves up from the leg towards the back (called centralisation).
  • Stop and check with a clinician: pain spreads further down the leg, or new numbness, tingling or weakness appears.

 

Start with 1–2 exercises, a few times a day, and add more as they feel easy.

 

1. Pelvic tilt. Lie on your back with knees bent. Gently tighten your stomach and flatten your lower back into the floor. Hold 3–5 seconds, relax, and repeat 8–10 times. Useful early on when most movements hurt.

 

2. Prone press-up (McKenzie extension). Lie face down. Place your hands under your shoulders and gently press your upper body up, keeping your hips on the floor. Lower slowly; repeat 8–10 times. Helpful for many people with disc-related leg pain, but only continue if symptoms ease or centralise.

 

3. Glute bridge. Lie on your back with knees bent and feet flat. Press through your heels and lift your hips until your body is in a straight line from shoulders to knees. Lower with control; 8–12 repetitions.

 

4. Bird-dog. On hands and knees, extend one arm forward and the opposite leg back, keeping your back level. Hold 3–5 seconds, then switch sides; 6–8 per side.

 

5. Side-lying clamshell. Lie on your side, knees bent and feet together. Lift the top knee without rolling your hips back. Lower slowly; 10–15 per side.

 

6. Walking. Short, frequent walks are often better tolerated than one long walk. Add a few minutes every couple of days if symptoms allow.

Movements to strictly avoid while symptoms are active

Avoid these until your leg symptoms have settled and your physiotherapist clears them. Repeated bending and loaded twisting are the movements most likely to aggravate disc-related leg pain.

 

  • Sit-ups and crunches: repeated loaded forward bending.
  • Toe touches and seated forward bends: stretch an irritated nerve and bend the spine forward.
  • Heavy lifting from the floor, especially with a twist: high load on the lower discs.
  • Knee-to-chest pulls if they send pain down the leg: fine for some people, aggravating for others.
  • High-impact running or jumping early on: reintroduce gradually in the strengthening phase.
  • Any exercise that spreads pain further down the leg or brings on new numbness or weakness.

 

For a longer list of options, see our best exercises for lower back pain and disc bulges.

Daily habits that help recovery

Break up sitting every 30–45 minutes, walk daily, sleep with a pillow between or under your knees, and avoid bed rest beyond a day or two.

 

  • Sitting: keep sitting spells shorter (about 30–45 minutes), with feet flat and a small lumbar support. Stand and walk for a minute or two between spells.
  • Sleeping: lie on your side with a pillow between your knees, or on your back with a pillow under your knees. Choose a mattress you find comfortable; there is no single best type.
  • Lifting: keep loads close to your body, bend at the hips and knees, and avoid twisting while lifting until you are stronger.
  • Bed rest: avoid it beyond a day or two. Gentle movement helps more than rest.
  • Work: staying at or returning to work with adjustments usually helps recovery.

Week-by-Week Recovery Timeline: How Long Does an L4-L5 Bulge Take to Heal?

Most people feel clearly better within 6–12 weeks. Nerve symptoms such as numbness can take longer, and a full return to heavy work or sport can take 3 months or more.

 

Everyone’s recovery is different, and flare-ups along the way are common. A typical pattern looks like this:

Typical recovery phases for low back pain. Progress depends on symptoms, function and individual clinical assessment rather than fixed deadlines.
Phase Typical timing Focus
Settling Weeks 0–2 Calm the pain: find comfortable positions, take short walks and avoid prolonged sitting.
Restoring movement Weeks 2–6 Try appropriate directional exercises, begin core and hip exercises, and gradually increase walking duration.
Strengthening Weeks 6–12 Build strength progressively, practise lifting mechanics and return towards normal daily activities.
Returning fully 3 months+ Gradually return to sport or heavy work and establish a long-term maintenance programme.

Many people feel clearly better within 6–12 weeks. Nerve symptoms such as numbness can take longer to settle than pain. If you are not improving after about 6 weeks of good care, ask your clinician to reassess you.

L4-L5 Disc Bulge Recovery Case Study (Resolve360 Patient)

Ashish, 38, software engineer. Mark sat at a desk about 9 hours a day and developed sharp sciatica and lower back stiffness. His MRI showed an L4-L5 disc bulge affecting the left L5 nerve root.

Illustrative recovery timeline showing treatment activities and reported changes over time.
Weeks What we did What changed
1–2 Symptom-easing positions, short walks and workstation changes. Pain became more manageable, although sitting remained limited.
3–6 Directional exercises, core and glute strengthening, and longer walks. Leg pain eased and sitting tolerance improved.
7–10 Progressive strengthening, posture guidance and lifting practice. Returned to weekend hiking; leg numbness resolved by week 10.

If Surgery Is Recommended

Surgery is usually considered only when severe leg pain does not improve with non-surgical care, if leg weakness is getting worse, or in medical emergencies like cauda equina syndrome.

 

The most common operation is a microdiscectomy, which removes the part of the disc pressing on the nerve. While it can relieve leg pain faster, it does not replace the need for rehabilitation. If you do have an operation, check out our guide on physical therapy after back surgery.

 

Note: Disc bulges and herniations are managed differently in some cases. If your MRI report says “herniation,” “extrusion,” or “protrusion,” read our specific guide: Can physical therapy fix a herniated disc without surgery?

Start Your Recovery: Getting Help From Resolve360

Resolve360 offers expert, one-to-one virtual physical therapy (physiotherapy) by live video, accessible from the comfort of your home—whether you are in India or accessing care globally.

 

Unlike automated exercise apps, we don’t hand you a generic program or a chatbot. Here is how we help you heal safely:

 

  • Live Sessions with Senior Experts: Every session is a 1-on-1 video call with an in-house physiotherapist bringing 10 to 30+ years of clinical experience. They watch how you move, adjust your routine, and decide when you are ready to progress.

  • Patented AI Movement-Tracking: Worried about doing your back exercises incorrectly at home? Our app uses cutting-edge AI (Indian Patent No. 596041) to analyze your biomechanics and correct your form in real-time for faster, safer recovery.

  • Complete Review & Transparent Pricing: We review your symptoms and MRI scans, and build a personalized plan starting with a completely free initial assessment (₹0). If needed, follow-up live sessions start at just ₹1,499.

  • Patient Safety Comes First: Your health is our priority. If your assessment shows you need an in-person examination, imaging, or a specialist, we will clearly advise you to see a local clinician.

 

Resolve360 has treated over 50,000+ patients and is available globally on the Apple App Store and Google Play.

Start With a ₹0 Free Consultation

Get a personalised 1-on-1 live video consultation with a physiotherapist. Live sessions are available for ₹1,499, with a recorded home-exercise plan for ₹499.

Your physiotherapist will assess your needs and guide you on the next appropriate step.

Frequently asked questions

Most people feel significant relief within 6 to 12 weeks with an active, guided physical therapy program. Some cases may take a few months, especially if nerve symptoms (like sciatica) are present. Note: The bulge may still appear on a later MRI even after your pain has completely resolved.

Yes, walking is highly recommended. It is one of the safest and best-tolerated activities for a disc bulge. Start with short, frequent walks on flat surfaces and build up gradually. If you feel pain spreading further down your leg, slow down and consult your physiotherapist.

Most people return to normal activities and stay pain-free. However, back pain can recur. Staying active and keeping up with core strengthening exercises reduces the chances of a flare-up and helps you maintain long-term spinal health.

In a disc bulge, the disc flattens and spreads out, but its tough outer ring stays intact. In a herniated disc (or slipped disc), the inner gel-like material pushes through a tear in the outer ring. Both can cause nerve pain and are usually treated without surgery first.

Studies show that heat therapy is generally more effective for soothing acute lower back pain and relaxing tight muscles. Use a heating pad for 15 to 20 minutes, placing a cloth between the pack and your skin to prevent burns.

Early in your recovery, you should avoid repeated forward bending, sit-ups, and heavy lifting, as these put direct pressure on the L4-L5 disc. You must also stop any exercise or movement that sends pain further down your leg.

Not always. Clinical guidelines advise getting an MRI only if your nerve symptoms are getting rapidly worse, if you have emergency “red flag” signs, or if you are planning for surgery. Many people have disc bulges on an MRI but experience absolutely no pain.

Absolutely. For most people without emergency warning signs, virtual care is highly effective. Platforms like Resolve360 offer live, 1-on-1 video sessions with senior physiotherapists and use patented AI movement-tracking to ensure your exercise form is perfect—helping you heal safely from home.

The best sleeping position is usually on your side in a fetal position with a pillow between your knees. This keeps your spine in a neutral alignment and relieves pressure on the L4 and L5 nerve roots. If you prefer sleeping on your back, place a pillow under your knees. You should generally avoid sleeping on your stomach, as it arches the lower back and increases disc pressure.

Yes, but you must take frequent breaks. Prolonged sitting puts significantly more pressure on your lower lumbar discs compared to standing or walking. If you have a desk job, use a chair with strong lumbar support, keep your feet flat on the floor, and make sure to stand up, walk, or stretch every 30 to 45 minutes.

No, a massage cannot push a bulging disc back into place. While deep tissue massage can provide temporary relief from muscle spasms and stiffness in your lower back, it does not heal the underlying disc issue. For genuine, long-term recovery, you need an active physical therapy program to build core strength and stabilize the spine.

meet your expert

Dr. Apoorva Shrivastava

Dr. Apoorva Shrivastava is a senior physical therapist, clinical rehabilitation leader and Founder & CEO of Resolve360 with 20+ years of experience in physiotherapy and rehabilitation. She has supported 50,000+ patients globally and has experience across 250+ conditions, including chronic pain, sciatica, disc bulge, frozen shoulder, cervical spondylosis, lumbar spondylosis, back pain, neck pain, shoulder pain and knee pain. She holds a Bachelor’s in Physiotherapy from Saveetha Medical College and a Master’s in Advancing Physiotherapy from Sheffield Hallam University, UK, with a major focus on Neuro Physiotherapy. Her experience includes St Helier’s Hospital, NHS, UK, PAN-India clinical training and leadership involving 500+ physical therapist across India.

Specialization

Neurological Physiotherapy, Spine Rehabilitation, Chronic Pain Rehabilitation and Musculoskeletal Rehabilitation

Clinical Experience​

17+ Years of Physiotherapy & Rehabilitation Experience

Qualification

BPT – Saveetha Medical College; Master’s in Advancing Physiotherapy – Sheffield Hallam University, UK

Professional Registration

Indian Association of Physiotherapists (IAP) Member – I.A.P. No. 69959

Clinical Expertise

Neurological Rehabilitation, Chronic Pain, Spine & Musculoskeletal Rehabilitation

Working Experience

St Helier’s Hospital, NHS, UK; PAN-India Clinical Training & Rehabilitation Leadership

Patent & Innovation

Named Inventor – Resolve360’s Indian Patented Rehabilitation Methodology | Patent No. 596041

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I came across a Resolve360 ad and decided to give them a try for my knee pain. I contacted them, and their team got in touch with me and explained everything clearly. I had my online physiotherapy session with Dr. Sandeep, and I had a really good experience. He was patient, friendly, and took the time to understand my pain and daily routine before suggesting exercises. He explained each exercise properly and showed me how to do the movements correctly. I could also ask questions during the session, which made things much easier. I really liked the convenience of doing the sessions from home. I didn’t have to travel to a clinic, and the one-on-one sessions felt personal and comfortable. The follow-up sessions were also helpful and kept me motivated to stay consistent with the exercises. A special thanks to Dr. Sandeep for being so supportive and easy to talk to. He made the whole process feel simple and comfortable. Overall, I’m happy with my experience with Resolve360 and would recommend them to anyone looking for convenient online physiotherapy.
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I am currently recovering from ACL reconstruction surgery, and choosing the Resolve360 video rehabilitation platform has been one of the best decisions for my recovery journey. When I joined the platform, I was not only recovering from surgery but was also suffering from severe back pain that significantly limited my mobility. Surprisingly, after just two sessions, I experienced noticeable relief in my back pain, which gave me the confidence to continue my rehabilitation. What I appreciate the most is that every exercise is carefully tailored to my specific condition, recovery stage, and individual needs. The structured rehabilitation plan has kept me consistent and motivated. Without this platform, I don't think I would have had such a well-organized approach to my recovery. A special thanks to Dr. Diksha for her exceptional expertise. She has an incredible ability to understand the root cause of pain and provide effective solutions, even through remote consultations. Beyond her clinical skills, she is incredibly empathetic, patient, and motivating. She genuinely listens, understands what you're going through, and encourages you throughout the recovery process, making even the most challenging phases feel manageable. Her guidance and positive attitude have been invaluable to my recovery. I would also like to appreciate my Care Manager, Ms. Aditi, for her outstanding support. She is extremely proactive and dedicated to ensuring everything runs smoothly. Whether it's reminding me to schedule my diet consultation or reassessment sessions, handling last-minute rescheduling, or assisting with payments, she manages every aspect effortlessly. She is always responsive and just a chat away whenever I need help. I highly recommend Resolve360 to anyone looking for a personalized, structured, and professionally managed rehabilitation program. The combination of expert physiotherapy and exceptional customer support has made my recovery journey much smoother and more reassuring.
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The Only Solution That Found My Root Cause and Delivered Real Recovery ​For years, I was trapped in a frustrating cycle, suffering from debilitating back pain and a persistent knee injury. I had seen countless specialists—various physiotherapists and chiropractors—but none of them could provide lasting relief or truly get to the heart of my problems. I was ready to give up. ​Thankfully, Dr. Apoorva and Dr. Asish insisted I join Resolve 360 for a fresh start on my recovery journey, and it was the best decision I could have made. ​The true breakthrough came from Dr. David. His diagnostic skill is exceptional; during our dedicated one-on-one video call sessions, he was able to accurately find and address the root cause of both my back pain and knee instability. For the first time, I felt like I wasn't just treating symptoms, but actually correcting the underlying issues. ​The progress has been incredible. My initial back and knee pain are vastly improved, and Resolve 360 continues to help me, focusing now on making my muscles strong to ensure long-term stability and health. The one-on-one format is the key—it ensures I receive personalized attention, correct technique, and real-time adjustments tailored only to me. ​If you have tried multiple avenues without success, I highly recommend Resolve 360. Their expert team, especially Dr. David, Dr. Apoorva, and Dr. Asish, offers a level of insight and dedicated care that truly resolves problems. This service is a game-changer!
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I am suffering from heel pain for the last few years and the physiotherapy sessions provided by resolve360 have helped me a lot. The best thing about resolve360 is the flexibility they offer. I had sessions both early in the morning and evening depending upon my schedule. All the doctors on their panel are excellent and are always willing to go extra mile and give more than 100%. They do not prescribe any short cuts and focus on resolving the problem from the root cause instead of promising you any magic pill. I will recommend everyone to give it a try if they are facing any issues related to pain or mobility and is in need of physiotherapy.
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I was introduced to Resolve 360 by a close friend who have been your patients for some time now. I too am a Resolve patient for some time now for Back and Knee pain issues. I can confidently say that I am in safe n sure hands and my pain score has come down to 5 on a scale of 10 and that I may not have to go for TKR. I must mention that Dr. Mohit, Dr. Renuka and now Dr. Ankita are super powers for me by way of treatment and encouragement!! Great n effective sessions indeed.
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I am Dr.Shailesh Patel (obstetrician and gynaecologist) from Maharashtra. I had rotator cuff muscle injury. I was not able to do my Surgeries and had severe pain during sleep also. I consulted many Ortho and Joint surgeons. I also tried physiotherapy treatment for 2 months in my local place. But no results. I stopped my regular surgeries and was very depressed, worried about my illness. I searched for online option. I came across Resolve 360. Right from my first consultation, assessment session whole team of doctors from Resolve 360 helped me very kindly and patiently. I started getting relief in my first week of physiotherapy sessions. Now after 10 weeks I am completely relieved from my pain. I started doing all my routine surgeries and also strength training. I am very satisfied and happy with whole team. I am very thankful to all team members of Resolve 360 for helping me to come out of my illness and rejoining my work which is my passion and only earning source for my family. Thank you all especially Dr.Ankita , I will be always greatful for your help.
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